Prof. Dr. Rüdiger Klapdor

كبير الأطباء, طب أمراض النساء, مستشفى ألبرتينان
كبير الأطباء, التوليد, مستشفى ألبرتينان

Practical Experience

From 08/2023	Head of the department for Gynecology and Obstetrics, Albertinen Hospital Hamburg
01/2019 – 08/2023	Senior physician, Department of Gynaecology and Obstetrics, Hannover Medical School
06/2018 - 07/2018	Voluntary work as gynecologist in Serabu community hospital, Sierra Leone, German Doctors e.V.
01/2013 –12/2018	Resident in the Department of Gynaecology and Obstetrics, Hannover Medical School

Academic Research

02/2023-08/2023	W2-professor for translational gynecologic oncology, Hannover Medical School
10/2022	Appointment as adjunct professor, Hannover Medical School
01/2013 – 04/2018	Habilitation thesis, Sentinel lymph node dissection in gynaecological cancer
09/2013 – to date	Experimental research on adoptive immunotherapy using Chimeric Antigen Receptors (CAR) against ovarian cancer in cooperation with Prof. Dr. Dr. Axel Schambach, Institute of Experimental Hematology, Hannover Medical School
08/2010 – 04/2015	Doctorate, Thesis on ‘LeGO-Switch, new versatile, inducible lentiviral All-In-One vectors for exact and reliable doxycycline dependent gene expression’, Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Centre Hamburg-Eppendorf, final grade: magna cum laude

Education

08/2023	Specialist certificate in gynecologic oncology
08/2020	Certified as surgeon for the DaVinci robotic system
04/2020	Specialist certificate in obstetrics and perinatal medicine
03/2019 – 04/2023	University Hamburg, MBA health management
10/2006 – 10/2012	University Medical Centre Hamburg-Eppendorf, Hamburg Study of human medicine: 1.3 (final grade) Preliminary medical examination (Physikum): 1.0 (final grade) Elective subject Experimental Oncology: 1.0 (final grade) Elective subject Introduction to Molecular Medicine: 1.0 (final grade)
09/1998 – 07/2006	Gelehrtenschule des Johanneums, Hamburg Abitur equivalent to A-Levels: 1.0 (final grade)

Fellowship and academic distinctions

10/2022	Lecture award at the biennial congress of the DGGG Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.
10/2020	Lecture award at the biennial congress of the DGGG Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.
10/2020	Poster award at the biennial congress of the DGGG Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.
09/2019	‘Hans-Frangenheim-Preis‘ by the AGE ‘Arbeitsgemeinschaft gynäkologische Endoskopie’, 1500€
06/2019	‘Leuchtfeuer des Nordens’, by the NGGG for the best abstract ‘Norddeutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.’, 500€
05/2019	ASTA teacher award regarding the fourth educational year Hannover Medical School
09/2017	‘Staude-Pfannenstiel award’ by the NGGG for the best unpublished manuscript ‘Norddeutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.’, 2500€
10/2016	Lecture award at the biennial congress of the DGGG ‚Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.‘
01/2016 – 12/2018	Admission to the ‘Junge Akademie‘ at the MHH. A clinical scientist program including financial support and rotations into research departments.
10/2015 – 10/2017	Admission to ‘TRAIN Academy, Translational Research & Medicine: From Idea to Product’
08/2015 – 08/2016	Research promoting grant, 18.800€ ‘Hochschulinterne Leistungsförderung‘, Hannover Medical School
12/2014	‘Young Teacher Award’ regarding the fourth educational year Hannover Medical School
12/2006 – 12/2012	Fellowship of the German National Academic Foundation ‘Studienstiftung des deutschen Volkes e.V. ‘
06/2006	‘Bugenhagen medal’, Award for the best Abitur Gelehrtenschule des Johanneums, Hamburg

Publications

1.1. First or last author

1.1.1. Klapdor R, Mücke J, Schneider M, Länger F, Gratz KF, Hillemanns P, Hertel H. Value and advantages of preoperative sentinel lymph node imaging with SPECT/CT in cervical cancer. Int J Gynecol Cancer. 2014 Feb;24(2):295-302. doi:10.1097/IGC.0000000000000032. (IF 1.958)

1.1.2. Mücke J*, Klapdor R*, Schneider M, Länger F, Gratz KF, Hillemanns P, Hertel H. Isthmocervical labelling and SPECT/CT for optimized sentinel detection in endometrial cancer: technique, experience and results. Gynecol Oncol. 2014 Aug;134(2):287-92. doi: 10.1016/j.ygyno.2014.05.001. * shared first author (IF 3,774)

1.1.3. Klapdor R, Länger F, Gratz KF, Hillemanns P, Hertel H. SPECT/CT for SLN dissection in vulvar cancer: Improved SLN detection and dissection by preoperative three-dimensional anatomical localisation. Gynecol Oncol. 2015 Sep;138(3):590-6. doi: 10.1016/j.ygyno.2015.06.011. (IF 4,198)

1.1.4. Hillemanns P, Wimberger P, Reif J, Stepp H, Klapdor R. Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. Lasers Surg Med. 2016 Nov 16. doi: 10.1002/lsm.22613. (IF 2,503)

1.1.5. Klapdor R, Hertel H, Soergel P, Hillemanns P. Groin Recurrences in Node Negative Vulvar Cancer Patients After Sole Sentinel Lymph Node Dissection. Int J Gynecol Cancer 2017 Jan;27(1):166-170. doi: 10.1097/IGC.0000000000000860. (IF 2,192)

1.1.6. Klapdor R, Hillemanns P, Wölber L, Jückstock J, Hilpert F, de Gregorio N, Iborra S, Sehouli J, Habermann A, Fürst ST, Strauß HG, Baumann K, Thiel F, Mustea A, Meier W, Harter P, Wimberger P, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Richter B, Jäger M, Mahner S. Outcome After Sentinel Lymph Node Dissection in Vulvar Cancer: A Subgroup Analysis of the AGO-CaRE-1 Study. Ann Surg Oncol. 2016 Nov 28. (IF 4,200)

1.1.7. Klapdor R, Hertel H, Soergel P, Jentschke M, Hillemanns P. Application of sentinel lymph node dissection in gynecological cancers: results of a survey among German hospitals. Arch Gynecol Obstet. 2016 Dec 29. doi: 10.1007/s00404-016-4279-3. (IF 2,321)

1.1.8. Klapdor R, Grosse J, Hertel B, Hillemanns P, Hertel H. Postoperative anatomic and quality-of-life outcomes after vaginal sacrocolporectopexy for vaginal vault prolapse. Int J Gynaecol Obstet. 2017 Jan 6. doi: 10.1002/ijgo.12095. (IF 1,77)

1.1.9. Klapdor R, Wang S, Hacker U, Büning H, Morgan M, Dörk T, Hillemanns P, Schambach A. Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy. Hum Gene Ther. 2017 Aug 24. doi: 10.1089/hum.2017.168. (IF 4,419)

1.1.10. Klapdor R, Wang S, Morgan M, Dörk T, Hacker U, Hillemanns P, Büning H, Schambach A. Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer. Int J Mol Sci. 2019 Feb 3;20(3). pii: E660. doi:10.3390/ijms20030660 (IF 4,605)

1.1.11. Klapdor R, Wölber L, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Jückstock J, Hilpert F, de Gregorio N, Hillemanns P, Fürst ST, Mahner S. Predictive factors for lymph node metastases in vulvar cancer. An analysis of the AGO-CaRE-1 multicenter study. Gynecol Oncol. 2019 Jun 18. pii: S0090-8258(19)31324-1. doi: 10.1016/j.ygyno.2019.06.013 (IF 4.623)

1.1.12. Klapdor R, Hertel H, Hillemanns P, Röttger M, Soergel P, Kuehnle E, Jentschke M. Peritoneal contamination with ICG-stained cervical secretion as surrogate for potential cervical cancer tumor cell dissemination: A proof-of-principle study for laparoscopic hysterectomy. Acta Obstet Gynecol Scand. 2019 Jun 26. doi:10.1111/aogs.13681 (IF 2,770)

1.1.13. Klapdor, R., Hillemanns, P., Wölber, L., Jückstock, J., Hilpert, F., de Gregorio, N., Hasenburg, A., Sehouli, J., Fürst, S., Strauss, H., Baumann, K., Thiel, F., Mustea, A., Meier, W., Harter, P., Wimberger, P., Hanker, L., Schmalfeld, B., & Mahner, S. (2020). Association between obesity and vulvar cancer recurrence: an analysis of the AGO-CaRE-1 study. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 30(7), 920–926. doi.org/10.1136/ijgc-2019-001187 (IF 3,44)

1.1.14. Röttger, M., Hertel, H., Kaukemüller, L., Brodowski, L., Flentje, M., Hillemanns, P., & Klapdor, R. (2020). Sentinel lymph node biopsy in vulvar cancer: status, level of knowledge, and counseling in outpatient setting. Archives of gynecology and obstetrics, 10.1007/s00404-020-05701-4. Advance online publication. doi.org/10.1007/s00404-020-05701-4 (IF 2,670)

1.1.15. Klapdor R, Weiß C, Kuehnle E, Kohls F, von Ehr J, Philippeit A, Hille-Betz U. Quality of Life after Bilateral and Contralateral Prophylactic Mastectomy with Implant Reconstruction. Breast Care (Basel). 2020 Oct;15(5):519-526. doi: 10.1159/000505449. Epub 2020 Jan 24. PMID: 33223996; PMCID: PMC7650103. (IF 2,860)

1.1.16. Klapdor R, Hertel H, Delebinski L, Hillemanns P. Association of preoperative cone biopsy with recurrences after radical hysterectomy. Arch Gynecol Obstet. 2021 Jul 21. doi: 10.1007/s00404-021-06145-0. Epub ahead of print. PMID: 34291339. (2020 IF 2,670)

1.1.17. Klapdor R, Wang S, Morgan MA, Zimmermann K, Hachenberg J, Büning H, Dörk T, Hillemanns P, Schambach A. NK Cell-Mediated Eradication of Ovarian Cancer Cells with a Novel Chimeric Antigen Receptor Directed against CD44. Biomedicines. 2021 Sep 28;9(10):1339. doi: 10.3390/biomedicines9101339 PMID: 34680456; PMCID: PMC8533227. (IF 6.081)

1.1.18. Fard D, Borchers CS, Philippeit JC, Philippeit AV, Kaukemüller LR, Higgins-Wood LR, Papageorgiou S, Hillemanns P, von Kaisenberg CS, Klapdor R. Comparing forces on the fetal neck in breech delivery in lithotomy versus all-fours position: a simulation model. Arch Gynecol Obstet. 2022 Jul 20. doi: 10.1007/s00404-022-06671-5 Titel anhand dieser DOI in Citavi-Projekt übernehmen. Epub ahead of print. PMID: 35857095

1.1.19. Klapdor R, Kleine M, Schilling T, Huusmann S, Philippeit A, Philippeit J, Timrott K, Kruppa M, Hillemanns P, Imkamp F. SOCIUS Mentoring-A Novel Course to Encourage Students for a Career as Surgical Oncologists. Med Sci (Basel). 2022 Jun 24;10(3):35. doi: 10.3390/medsci10030035

And many additional articles, including articles as co author, reviews and non-listed articles and book chapters.